Suppressed Andreev Reflection at the Normal-Metal / Heavy-Fermion Superconductor CeCoIn5_5 Interface

Dynamic conductance spectra are taken from Au/CeCoIn$_5$ point contacts in the Sharvin limit along the (001) and (110) directions. Our conductance spectra, reproducibly obtained over wide ranges of temperature, constitute the cleanest data sets ever reported for HFSs. A signature for the emerging heavy-fermion liquid is evidenced by the development of the asymmetry in the background in the normal state. Below $T_c$, an enhancement of the sub-gap conductance arising from Andreev reflection is observed, with the magnitude of $\sim$ 13.3 % and $\sim$ 11.8 % for the (001) and the (110) point contacts, respectively, an order of magnitude smaller than those observed in conventional superconductors but consistent with those in other HFSs. Our zero-bias conductance data for the (001) point contacts are best fit with the extended BTK model using the d-wave order parameter. The fit to the full conductance curve of the (001) point contact indicates the strong coupling nature ($2\Delta/k_{B}T_c = 4.64$). However, our observed suppression of both the Andreev reflection signal and the energy gap indicates the failure of existing models. We provide possible directions for theoretical formulations of the electronic transport across an N/HFS interface. Several qualitative features observed in the (110) point contacts provide the first clear spectroscopic evidence for the $d_{x^2-y^2}$ symmetry.Comment: 13 pages, 7 figures, LaTeX, paper invited and submitted to SPIE Conference on Strongly Correlated Electron Materials: Physics and Nanoengineering, in San Diego, California, July 31 - August 4, 200

Desmoglein 3 acts as a potential oncogene in promoting cancer cell migration and invasion through regulating AP-1 and PKC dependent-Ezrin activation

Conference: 20th Anniversary Conference of the British-Skin-Foundation on Skin Deep - 20 Years of Research Location: Roayl Coll Phys, London, ENGLAND Date: OCT 13, 2016British Skin Fd

Seasonal and spatial dynamics of the primary vector of plasmodium knowlesi within a major transmission focus in Sabah, Malaysia

Background The simian malaria parasite Plasmodium knowlesi is emerging as a public health problem in Southeast Asia, particularly in Malaysian Borneo where it now accounts for the greatest burden of malaria cases and deaths. Control is hindered by limited understanding of the ecology of potential vector species. Methodology/Principal Findings We conducted a one year longitudinal study of P. knowlesi vectors in three sites within an endemic area of Sabah, Malaysia. All mosquitoes were captured using human landing catch. Anopheles mosquitoes were dissected to determine, oocyst, sporozoites and parous rate. Anopheles balabacensis is confirmed as the primary vector of. P. knowlesi (using nested PCR) in Sabah for the first time. Vector densities were significantly higher and more seasonally variable in the village than forest or small scale farming site. However An. balabacensis survival and P. knowlesi infection rates were highest in forest and small scale farm sites. Anopheles balabacensis mostly bites humans outdoors in the early evening between 1800 to 2000hrs. Conclusions/Significance This study indicates transmission is unlikely to be prevented by bednets. This combined with its high vectorial capacity poses a threat to malaria elimination programmes within the region. Author Summary The first natural infection of Plasmodium knowlesi was reported 40 years ago. At that time it was perceived that the infection would not affect humans. However, now P. knowlesi is the predominant malaria species (38% of the cases) infecting people in Malaysia and is a notable obstacle to malaria elimination in the country. Plasmodium knowlesi has also been reported from all countries in Southeast Asia with the exception of Lao PDR and Timor Leste. In Sabah, Malaysian Borneo cases of human P. knowlesi are increasing. Thus, a comprehensive understanding of the bionomics of the vectors is required so as to enable proper control strategies. Here, we conducted a longitudinal study in Kudat district, Sabah, to determine and characterize the vectors of P. knowlesi within this transmission foci. Anopheles balabacensis was the predominant mosquito in all study sites and is confirmed as vector for P. knowlesi and other simian malaria parasites. The peak biting time was in the early part of the evening between1800 to 2000. Thus, breaking the chain of transmission is an extremely challenging task for the malaria elimination programme

Theory of the "honeycomb chain-channel" reconstruction of Si(111)3x1

First-principles electronic-structure methods are used to study a structural model for Ag/Si(111)3x1 recently proposed on the basis of transmission electron diffraction data. The fully relaxed geometry for this model is far more energetically favorable than any previously proposed, partly due to the unusual formation of a Si double bond in the surface layer. The calculated electronic properties of this model are in complete agreement with data from angle-resolved photoemission and scanning tunneling microscopy.Comment: 4 pages, 4 figures, submitted to Phys. Rev. Lett (the ugly postscript error on page 4 has now been repaired

Efficient Photon Coupling from a Diamond Nitrogen Vacancy Centre by Integration with Silica Fibre

A central goal in quantum information science is to efficiently interface photons with single optical modes for quantum networking and distributed quantum computing. Here, we introduce and experimentally demonstrate a compact and efficient method for the low-loss coupling of a solid-state qubit, the nitrogen vacancy (NV) centre in diamond, with a single-mode optical fibre. In this approach, single-mode tapered diamond waveguides containing exactly one high quality NV memory are selected and integrated on tapered silica fibres. Numerical optimization of an adiabatic coupler indicates that near-unity-efficiency photon transfer is possible between the two modes. Experimentally, we find an overall collection efficiency between 18-40 % and observe a raw single photon count rate above 700 kHz. This integrated system enables robust, alignment-free, and efficient interfacing of single-mode optical fibres with single photon emitters and quantum memories in solids

Classification of Overlapped Audio Events Based on AT, PLSA, and the Combination of Them

Audio event classification, as an important part of Computational Auditory Scene Analysis, has attracted much attention. Currently, the classification technology is mature enough to classify isolated audio events accurately, but for overlapped audio events, it performs much worse. While in real life, most audio documents would have certain percentage of overlaps, and so the overlap classification problem is an important part of audio classification. Nowadays, the work on overlapped audio event classification is still scarce, and most existing overlap classification systems can only recognize one audio event for an overlap. In this paper, in order to deal with overlaps, we innovatively introduce the author-topic (AT) model which was first proposed for text analysis into audio classification, and innovatively combine it with PLSA (Probabilistic Latent Semantic Analysis). We propose 4 systems, i.e. AT, PLSA, AT-PLSA and PLSA-AT, to classify overlaps. The 4 proposed systems have the ability to recognize two or more audio events for an overlap. The experimental results show that the 4 systems perform well in classifying overlapped audio events, whether it is the overlap in training set or the overlap out of training set. Also they perform well in classifying isolated audio events